Reaching New Lights: How Partial Vision Has Been Restored To a Blind Patient

By Elizabeth Hallissey, C2ST Intern, Loyola University

A new gene-based therapy, known as optogenetic therapy, has led to the partial recovery of a blind man’s vision.

The 58-year-old patient has a genetic eye disease known as retinitis pigmentosa, which causes light receptor cells in the eyes to die, eventually leading to permanent blindness. In an effort to combat the retinitis pigmentosa, researchers used optogenetic therapy on the patient, taking damaged eye cells and altering them to make them fire in response to light. 

In the past decade, many therapies were used to slow the progression of this disease but none have attempted to restore sight to those who were already fully blind. Unlike other treatments, optogenetic therapy can be used to treat several different degenerative diseases.

The process works by injecting a virus known as an adeno-associated virus into the ganglion cells of a patient’s eyes. Viruses like these are naturally occurring, and are typically used to communicate information to the cells they are injected into. The virus carries instructions for the production of protein-making cells required for vision. Once the proteins are in place, they are then activated by light.

In the beginning of the research, this process came with complications–it was found that original use of bright blue light could do its own damage to the eye. To fix this problem, researchers decided to use a softer amber light that was easier on the eyes. To deliver this amber light, researchers outfitted the patient with goggles that repeatedly sent pulses of the amber light to activate the protein. Eventually, the patient’s vision was enhanced to the point that they could recognize objects like books, mugs, and the lines on the street.  

At this point in time, the therapy does not restore full vision. But the researcher are confident that with further testing the process will only become more effective. 

60 thoughts on “Reaching New Lights: How Partial Vision Has Been Restored To a Blind Patient

  1. Very interesting and well written. Hopefully there are people out there who can use this therapy to get their sight back some day. Great job Elizabeth!

  2. Undeniably believe that which you stated. Your favorite reason appeared to be on the net the
    easiest thing to be aware of. I say to you, I certainly get annoyed while people consider worries that they
    plainly don’t know about. You managed to hit the nail upon the
    top and also defined out the whole thing without having side-effects ,
    people can take a signal. Will probably be back to get
    more. Thanks

  3. I think that is among the most significant information for me.
    And i’m satisfied studying your article. But want
    to remark on some common issues, The site taste is
    great, the articles is truly nice : D. Good task, cheers

  4. When I originally commented I seem to have clicked the -Notify me
    when new comments are added- checkbox and from now on each time a comment is added I recieve four emails with the exact same comment.
    Is there an easy method you are able to remove me from that service?
    Thank you!

  5. I’ve recently started a blog, the info you offer on this web site has helped me tremendously. Thank you for all of your time & work. “Men must be taught as if you taught them not, And things unknown proposed as things forgot.” by Alexander Pope.

  6. Hello there! This is kind of off topic but I need some guidance from an established blog.

    Is it hard to set up your own blog? I’m not very techincal but I can figure things
    out pretty fast. I’m thinking about creating my own but I’m not
    sure where to start. Do you have any points or suggestions?
    Thanks

  7. What i don’t understood is actually how you are now not actually a lot more neatly-preferred than you might be right now. You are so intelligent. You already know therefore significantly relating to this topic, made me for my part consider it from a lot of numerous angles. Its like men and women are not interested until it is something to accomplish with Girl gaga! Your personal stuffs excellent. Always maintain it up!

  8. Thanks for the sensible critique. Me & my neighbor were just preparing to do a little research about this. We got a grab a book from our local library but I think I learned more from this post. I am very glad to see such magnificent info being shared freely out there.

  9. Thanks for the good writeup. It in truth was a amusement account it.

    Look complicated to more added agreeable from you! By the way, how could we communicate?https://github.com/marynewton89,
    https://support.advancedcustomfields.com/forums/users/marynewton89/,
    https://www.instapaper.com/p/9533415,
    https://www.deviantart.com/marynewton89,
    https://en.gravatar.com/marynewton89,

    https://sketchfab.com/marynewton89,
    https://www.pearltrees.com/marynewton89,

    https://www.atlasobscura.com/users/dnite,
    https://peatix.com/user/10110611/view,
    https://www.goodreads.com/user/show/141811216-mary-newton,
    https://www.couchsurfing.com/people/mary-newton-4,

    https://ello.co/marynewton89,
    https://trello.com/marrynewton,
    https://profile.hatena.ne.jp/TerryHead/,

    http://www.authorstream.com/Marrynewton/,
    https://seekingalpha.com/user/55139967/comments,
    https://readthedocs.org/projects/dramas-nite/,
    https://wefunder.com/marycnewton,
    https://www.ultimate-guitar.com/u/marynewton89,
    https://www.mixcloud.com/marynewton89/,

    https://dzone.com/users/4641223/marynewton89.html,
    https://marynewton89.contently.com/,
    https://coolors.co/u/mary_newton,
    https://www.f6s.com/mary-newton,
    https://guides.co/p/mary-newton,
    https://knowyourmeme.com/users/marynewton89,
    https://nootheme.com/forums/users/marynewton89/,
    https://slides.com/marynewton89,
    https://devpost.com/dnite?ref_content=user-portfolio&ref_feature=portfolio&ref_medium=global-nav,
    https://gust.com/accelerators/marynewton89,
    https://triberr.com/marynewton89,

    https://www.lbbonline.com/dashboard/personal,
    https://mastodon.social/web/@marynewton89,
    https://www.woddal.com/marynewton89,
    https://godotengine.org/qa/user/marynewton89,
    https://cycling74.com/author/6177ba6e40219f219daa9cec,
    https://seedandspark.com/user/mary-newton,
    https://zeef.com/profile/mary.c.newton,
    https://www.speedrun.com/user/marynewton89,
    https://www.linkedin.com/in/mary-newton-08154b224,
    https://www.allmyfaves.com/marynewton89,
    https://beermapping.com/account/marynewton89,

    http://recipes.mentaframework.org/user/edit/164945.page,
    https://marynewton89.livejournal.com/profile,
    https://gitlab.freedesktop.org/marynewton89,
    https://androidforums.com/members/mary-newton.2149024/,
    https://www.misterpoll.com/users/2145646,
    http://www.good-tutorials.com/users/marynewton89,
    https://windowsforum.com/members/marynewton89.116927/#about,

    https://www.spreaker.com/user/15584357,
    https://forum.mobilelegends.com/home.php?mod=space&uid=849849&do=profile,
    https://www.prestashop.com/forums/profile/1713731-marynewton89/,
    https://myanimelist.net/profile/marynewton89,
    https://www.tripadvisor.com.sg/Profile/marynZ4836WP

Leave a Reply